In different parts of the world, people speak different languages ​​to each other. Some parts of the world are more linguistically rich and more than one language is spoken in those regions. The aim of this study was to evaluate and evaluate the executive functions of the brain including cognitive flexibility, selective attention and response inhibition in monolingual and bilingual male and female students of Bu Ali Sina University of Hamadan. This research has been done by descriptive and causal-comparative method using complex Stroop computer test. The statistical population selected for this study were bilingual and monolingual students of Bu Ali Sina University. The test was performed on 214 male and female students. Data obtained from 165 students were analyzed by independent t-test and one-way analysis of variance. The obtained results showed that there is a significant difference between gender and executive functions studied in this study. But there was no significant difference between bilingual and monolingual individuals with these functions. In this study, we concluded that gender affects the executive functions of the brain, but bilingualism and monolingualism do not affect the executive functions of the brain.