Positive cognitive behavioral therapy is an integrated approach in psychotherapy that combines cognitive behavioral therapy with solution-focused therapy and positive psychology. The aim of this study was to compare the effectiveness of positive cognitive behavioral therapy and traditional cognitive behavioral therapy on mental well-being and resilience in adolescents with depressive symptoms. This study was an experimental design with pretest and posttests with the control group. For this purpose, first, a depression scale was performed on male students. Among those students whose depression score was higher than the cutoff point, randomly, 17 were divided into the experimental group 1 (PCBT), 17 were divided into the experimental group 2 (CBT), and 17 were divided into the control group (without intervention). Then, scales of Subjective well-being of students and Connor and Davison resiliency were implemented as pretests. Then, interventions in experimental groups and no intervention in the control group were performed, and finally, the above scales were performed as posttests and follow-up. Results showed that students’ scores in subjective well-being and resiliency with PCBT were significantly higher than CBT and control groups. It seems that; PCBT can be more effective in enhancing positive performance components. It’s necessary that; further research should highlight this issue.